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Writer's pictureJeannie Collins Beaudin

Going Off Antidepressants


Benalmadena Beach

I've had a busy week here in Spain, so not much time to research and write a blog Well, really I've been visiting outdoor markets, watching Flaminco dancing, and exploring nearby villages of Mijas and Arroyo de la Miel... busy having fun!

But I did spend one morning reading, and came across an excellent article about antidepressants from Harvard Medical School that I’d like to share. It discusses how the medications work, how long they should be taken, why they can cause withdrawal symptoms, and what to do when you decide (in discussion with your doctor) that it’s time to stop taking them.

Doctors will sometimes recommend continuing antidepressants for years to prevent depression in those who have had multiple severe bouts. But 6 months of treatment is often considered long enough for a first episode. Side effects, like drowsiness, insomnia, headache or sexual dysfunction, that are tolerable when seeking relief from depression may become bothersome and unacceptable once a person is feeling better.

Withdrawal effects that are known to sometimes develop when discontinuing antidepressant medications -- called "antidepressant discontinuation syndrome" -- can easily be confused with a return of depression itself. Working closely with a doctor while gradually decreasing the dose of the antidepressant is important. A doctor will monitor to ensure any new symptoms are caused by withdrawal and not a return of depression. A gradual taper of the medication will often be prescribed to help to minimize any withdrawal effects. Occasionally a return to a previous, slightly higher dose will be used to ease symptoms before gradually decreasing again.

As a compounding pharmacist, I have made capsules of strengths between those commercially available to allow a more gradual dose decrease in sensitive individuals. But often withdrawal can be managed by using tablets that can be cut, liquids that can be measured in small amounts, or by switching to longer acting medications that are cleared from the body more slowly.

If you, or someone you know, is considering stopping a long term antidepressant medication, I’d encourage you to read more about going off antidepressants here And be sure to work closely with your doctor and your pharmacist to ensure this change is accomplished safely and as comfortably as possible.

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